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Article

Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association.

The Journal of clinical endocrinology and metabolism - 1 Mar 2007

Owen Catherine J, Kelly Hannah, Eden James A, Merriman Marilyn E, Pearce Simon H S, Merriman Tony R

Abstract excerpt

CONTEXT: A four-marker haplotype in the 5' region of the Fc receptor-like 3 gene (markers FCRL3_3 to FCRL3_6) has been identified recently as contributing to rheumatoid arthritis (RA) susceptibility in the Japanese population. The promoter FCRL3_3*C allele also showed significant association with autoimmune thyroid disease and systemic lupus erythematosus. These findings raise the possibility that this locus may...

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Source

Identifiers

PMID: 17200162
DOI: 10.1210/jc.2006-2183

Genes

FCRL3
FCRL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association.PMID 17200162Read ↗

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Is FCRL3 a new general autoimmunity gene?Semantic proximity Read ↗

FCRL3 gene polymorphisms as risk factors for rheumatoid arthritis.Semantic proximity Read ↗

Analysis of Fcgamma receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B.Semantic proximity Read ↗

The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases.Semantic proximity Read ↗

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