Article
[Tyrosine kinase mutation and acute myeloid leukemia with T (8; 21)].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2009
Han Yang-Li, Zhang Su-Jiang, Qiao Chun, Dai Dan, Sun Xue-Mei, Xu Yan-Li, Qian Si-Xuan, Xu Wei, Wang Ji-Shi, Li Jian-Yong
Abstract excerpt
This study was aimed to investigate the status of c-KIT, Fms-like tyrosine kinase 3 (FLT3) and Janus kinase 2 (JAK2) mutations in acute myeloid leukemia (AML) patients with t (8; 21) and to analyze their relation to clinical feature and prognosis. PCR, AS-PCR, restriction and sequencing methods were used respectively to detect the FLT3, JAK 2 and c-KIT mutations in 8 cases of de novo AML with t (8; 21) and 6...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
