Article
[Association between melanocortin 4 receptor gene polymorphisms and obesity].
Zhonghua yi xue za zhi - 9 Jan 2007
Zhang Rong, Jia Wei-Ping, Hu Cheng, Wang Cong-Rong, Fang Qi-Chen, Bao Yu-Qian, Lu Jun-Xi, Ma Xiao-Jing, Xu Jing, Lu Hui-Juan, Xiang Kun-San
Abstract excerpt
OBJECTIVE: To investigate the association between the polymorphisms of melanocortin-4 receptor (MC4R) gene and obesity. METHODS: The genotypes of three polymorphisms, nt-216C/T, nt-178A/C, and Val103Ile, were determined through DNA sequencing in 563 Chinese from Shanghai, including 258 individuals with body mass index (BMI) over 30 kg/m(2) and 305 individuals with BMI less than 23 kg/m(2). Height and body weight...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Body Mass Index
- China
- Female
- Gene Frequency
- Genotype
- Humans
- Lipids
- Logistic Models
