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Article

Transforming growth factor-β: multifunctional regulator of differentiation and development

12 Mar 1990

Abstract excerpt

Transforming growth factors-beta (TGF-beta) are 25 kilodalton (kDa) homodimeric peptides with multifunctional actions controlling the growth, differentiation and function of a broad range of target cells of both epithelial and mesenchymal derivation. They are expressed early in embryogenesis and their tissue-specific and developmentally dependent expression is strongly suggestive of an essential role in...

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PMID: 1969655
DOI: 10.1098/rstb.1990.0050

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