Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis.

doi:10.1016/0165-5728(90)90140-i

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Article

Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis.

Journal of neuroimmunology - 1 Apr 1990

Fugger L, Morling N, Sandberg-Wollheim M, Ryder L P, Svejgaard A

Abstract excerpt

The NcoI tumor necrosis factor (TNF alpha) polymorphism was studied in relapsing/remitting multiple sclerosis and monosymptomatic optic neuritis. The frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were...

Topics

Adolescent
Adult
Alleles
Child
Genes
Humans
Multiple Sclerosis
Optic Neuritis
Phenotype
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Tumor Necrosis Factor-alpha

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