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Article

Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis.

Journal of neuroimmunology - 1 Apr 1990

Fugger L, Morling N, Sandberg-Wollheim M, Ryder L P, Svejgaard A

Abstract excerpt

The NcoI tumor necrosis factor (TNF alpha) polymorphism was studied in relapsing/remitting multiple sclerosis and monosymptomatic optic neuritis. The frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls.

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1969423
DOI: 10.1016/0165-5728(90)90140-i

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis.PMID 1969423Read ↗

Tumor necrosis factor polymorphism in multiple sclerosis: no additional association independent of HLA.Semantic proximity Read ↗

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Tumor necrosis factor alpha-308 alleles in multiple sclerosis and optic neuritis.Semantic proximity Read ↗

Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product.Semantic proximity Read ↗

TNF Nco-I RFLP is not an independent risk factor in rheumatoid arthritis.Semantic proximity Read ↗

[Analysis of two segments of biallelic polymorphism at the tumor necrosis factor in patients with multiple sclerosis from the Russian population: connection with NcoI-PDGF in the first intron of the lymphotoxin alpha gene].Semantic proximity Read ↗

Distribution of an NcoI polymorphism in the lymphotoxin alpha gene in Dutch patients with inflamatory bowel diseases.Semantic proximity Read ↗

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