Article
Genetic variation in the G72 (DAOA) gene affects temporal lobe and amygdala structure in subjects affected by bipolar disorder.
Bipolar disorders - 1 Sept 2009
Zuliani Riccardo, Moorhead T William J, Job Dominic, McKirdy James, Sussmann Jessika E D, Johnstone Eve C, Lawrie Stephen M, Brambilla Paolo, Hall Jeremy, McIntosh Andrew M
Abstract excerpt
BACKGROUND: Variation in the G72 (DAOA) gene is understood to convey susceptibility for bipolar disorder through an uncertain mechanism. Little is known about the structural brain phenotypes associated with this gene. We hypothesised that reductions in temporal lobe and amygdala gray matter would be associated with variation at two loci in the gene for which evidence of genetic linkage has been repeatedly...
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