Article
Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with bipolar disorder in two independent pedigree series.
American journal of human genetics - 1 May 2003
Hattori Eiji, Liu Chunyu, Badner Judith A, Bonner Tom I, Christian Susan L, Maheshwari Manjula, Detera-Wadleigh Sevilla D, Gibbs Richard A, Gershon Elliot S
Abstract excerpt
Linkage evidence suggests that chromosome 13 (13q32-33) contains susceptibility genes for both bipolar disorder and schizophrenia. Recently, genes called "G72" and "G30" were identified, and polymorphisms of these overlapping genes were reported to be associated with schizophrenia. We studied two series of pedigrees with bipolar disorder: the Clinical Neurogenetics (CNG) pedigrees (in which linkage to illness had...
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