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Article

Molecular properties of the glucosaminidase AcmA from Lactococcus lactis MG1363: mutational and biochemical analyses.

Gene - 15 Nov 2009

Inagaki Nobuya, Iguchi Akinori, Yokoyama Takahiro, Yokoi Ken-ji, Ono Yasushi, Yamakawa Ayanori, Taketo Akira, Kodaira Ken-Ichi

Abstract excerpt

The major autolysin AcmA of Lactococcus lactis ssp. cremoris MG1363 is a modular protein consisting of an N-terminal signal sequence, a central enzymatic region (glu(acma) as a glucosaminidase), and a C-terminal cell-recognition domain (LysM123). glu(acma) (about 160 amino acids) belongs to the glycoside hydrolase (GH) 73 family, and the two acidic residues E128 and D153 have been thought to be catalytically...

Topics

Amino Acid Sequence
Amino Acid Substitution
Base Sequence
Catalytic Domain
Cloning, Molecular
DNA, Bacterial
Genes, Bacterial
Lactococcus lactis
Molecular Sequence Data
Muramidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Site-Directed

Mutation

Oligonucleotide Probes

Recombinant Proteins

Sequence Homology, Amino Acid

Source

Identifiers

PMID: 19686822
DOI: 10.1016/j.gene.2009.08.004

Provenance

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