Article
Identification and molecular characterization of an N-Acetylmuraminidase, Aml, involved in Streptococcus mutans cell separation.
Microbiology and immunology - 1 Jan 2006
Yoshimura Goh, Komatsuzawa Hitoshi, Hayashi Ikue, Fujiwara Tamaki, Yamada Sakuo, Nakano Yoshio, Tomita Yuko, Kozai Katsuyuki, Sugai Motoyuki
Abstract excerpt
We previously demonstrated Streptococcus mutans produces two bacteriolytic enzymes of 100 kDa and 80 kDa (G. Yoshimura et al. Microbiol. Immunol. 48, 465-469, 2004). Here, we identified the protein sequence of these enzymes and found they come from a single gene product designated as automutanolysin (Aml). Aml has a modular design where the N-terminus contains five 13-amino-acid repeats and a C-terminal enzyme...
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