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Article

Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology.

Journal of neurochemistry - 1 Oct 2009

Danzer Karin M, Krebs Simon K, Wolff Michael, Birk Gerald, Hengerer Bastian

Abstract excerpt

Lewy bodies, alpha-synuclein (alpha-syn) immunopositive intracellular deposits, are the pathological hallmark of Parkinson's disease (PD). Interestingly, Lewybody-like structures have been identified in fetal tissue grafts about one decade after transplantation into the striatum of PD patients. One possible explanation for the accelerated deposition of alpha-syn in the graft is that the aggregation of alpha-syn...

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PMID: 19686384
DOI: 10.1111/j.1471-4159.2009.06324.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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