Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology.

Journal of neurochemistry - 1 Oct 2009

Danzer Karin M, Krebs Simon K, Wolff Michael, Birk Gerald, Hengerer Bastian

Abstract excerpt

Lewy bodies, alpha-synuclein (alpha-syn) immunopositive intracellular deposits, are the pathological hallmark of Parkinson's disease (PD). Interestingly, Lewybody-like structures have been identified in fetal tissue grafts about one decade after transplantation into the striatum of PD patients. O...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Cerebral Cortex
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Intermediate Filament Proteins

Share to Neuroblastoma

Share to Peptide Fragments

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 19686384
DOI: 10.1111/j.1471-4159.2009.06324.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19686384-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology.PMID 19686384Read ↗

In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategiesSemantic proximity Read ↗

Defined α-synuclein prion-like molecular assemblies spreading in cell cultureSemantic proximity Read ↗

<i>In vivo</i> phenotyping of Parkinson-specific stem cells reveals increased a-Synuclein levels but no spreadingSemantic proximity Read ↗

Cellular models of alpha‐synuclein toxicity and aggregationSemantic proximity Read ↗

Different species of alpha-synuclein oligomers induce calcium influx and seeding.Semantic proximity Read ↗

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in miceSemantic proximity Read ↗

The role of alpha-synuclein oligomerization and aggregation in cellular and animal models of Parkinson's disease.Semantic proximity Read ↗

Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talkSemantic proximity Read ↗

In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer SpeciesSemantic proximity Read ↗

α-Synuclein Oligomers Induce a Unique Toxic Tau StrainSemantic proximity Read ↗

Review: Spreading the word: precise animal models and validated methods are vital when evaluating prion‐like behaviour of alpha‐synucleinSemantic proximity Read ↗

Oligomers of α-synuclein: picking the culprit in the line-up.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.