Article
Association of Serotonin Transporter Gene (5-HTTLPR/rs25531) Polymorphism with Comorbidities of Panic Disorder.
Neuropsychobiology - 1 Jan 2021
Tanahashi Shunsuke, Tanii Hisashi, Konishi Yoshiaki, Otowa Takeshi, Sasaki Tsukasa, Tochigi Mamoru, Okazaki Yuji, Kaiya Hisanobu, Okada Motohiro
Abstract excerpt
INTRODUCTION: Panic disorder (PD) has many comorbidities such as depression, bipolar disorder (BPD), and agoraphobia (AG). PD is a moderately heritable anxiety disorder whose pathogenesis is not well understood. Recently, a tri-allelic serotonin transporter (5-HTTLPR/rs25531) polymorphism was reported to be more sensitive to personality traits compared to the bi-allelic 5-HTTLPR polymorphism. We hypothesized that...
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