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Article

Increased expression of DNA methyltransferase 3a in obese adipose tissue: studies with transgenic mice.

Obesity (Silver Spring, Md.) - 1 Feb 2010

Kamei Yasutomi, Suganami Takayoshi, Ehara Tatsuya, Kanai Sayaka, Hayashi Koji, Yamamoto Yuji, Miura Shinji, Ezaki Osamu, Okano Masaki, Ogawa Yoshihiro

Abstract excerpt

Epigenetic mechanisms are likely to be involved in the development of obesity. This study was designed to examine the role of a DNA methyltransferase (Dnmt3a), in obese adipose tissue. The gene expression of Dnmts was examined by quantitative real-time PCR analysis. Transgenic mice overexpressing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19680236
DOI: 10.1038/oby.2009.246

Genes

SFRP1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19680236-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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