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Article

Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.

PloS one - 12 Aug 2009

Jafar-Mohammadi Bahram, Groves Christopher J, Owen Katharine R, Frayling Timothy M, Hattersley Andrew T, McCarthy Mark I, Gloyn Anna L

Abstract excerpt

BACKGROUND: There is considerable interest in the hypothesis that low frequency, intermediate penetrance variants contribute to the proportion of Type 2 Diabetes (T2D) susceptibility not attributable to the common variants uncovered through genome-wide association approaches. Genes previously implicated in monogenic and multifactorial forms of diabetes are obvious candidates in this respect. In this study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19672314
DOI: 10.1371/journal.pone.0006615
PMCID: PMC2720540

Variants

rs61953349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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