Article
A promoter polymorphism of lamin A/C gene is an independent genetic predisposition to arterial stiffness in a Japanese general population (the Tanno and Sobetsu study).
Journal of atherosclerosis and thrombosis - 1 Aug 2009
Akasaka Hiroshi, Katsuya Tomohiro, Saitoh Shigeyuki, Sugimoto Ken, Ohnishi Hirofumi, Congrains Ada, Ohnishi Miyuki, Ohishi Mitsuru, Rakugi Hiromi, Ogihara Toshio, Shimamoto Kazuaki
Abstract excerpt
AIM: We examined the hypothesis that there is a positive, independent association between polymorphisms of lamin A/C gene (LMNA) and arterial stiffness in Japanese. METHODS: The subjects were 261 men (mean age, 64.4+/-0.7 years) selected from inhabitants of the towns of Tanno and Sobetsu in a rural area of Japan who underwent medical check-ups. We conducted clinical examinations, including measurement of...
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