Article
Clinicopathology and genetic profile of synchronous multiple small adenocarcinomas: implication for surgical treatment of an uncommon lung malignancy.
Annals of surgical oncology - 1 Aug 2014
Lin Mong-Wei, Wu Chen-Tu, Kuo Shuenn-Wen, Chang Yih-Leong, Yang Pan-Chyr
Abstract excerpt
PURPOSE: Synchronous multiple small adenocarcinomas are detected more frequently than in the past; however, the genetic profile, treatment, and prognosis of patients remain unclear. For treatment decisions and prognostic applications, we evaluated epidermal growth factor receptor (EGFR), p53, and KRAS somatic mutations in synchronous multiple small lung adenocarcinomas. METHODS: The presence of EGFR, p53, and...
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