Article
Carbonic anhydrase IX and human papillomavirus as diagnostic biomarkers of cervical dysplasia/neoplasia in women with a cytologic diagnosis of atypical glandular cells: a Gynecologic Oncology Group study in United States.
International journal of cancer - 15 Nov 2009
Liao Shu-Yuan, Rodgers William H, Kauderer James, Bonfiglio Thomas A, Walker Joan L, Darcy Kathleen M, Carter Randy, Hatae Masayuji, Levine Lyuba, Spirtos Nick M, Stanbridge Eric J
Abstract excerpt
High-risk human papillomavirus (H-HPV) infection is strongly linked to cervical neoplasia, but its role in detecting glandular lesions (GLs) is unclear. In the cervix, carbonic anhydrase IX (CA-IX) is expressed in cervical neoplasia, but rarely in the benign cervix. The diagnostic utility of these biomarkers was evaluated in women with a cytologic diagnosis of atypical glandular cells (AGC). H-HPV was detected...
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