Article
Carbonic anhydrase IX (CA-IX) and high-risk human papillomavirus (H-HPV) as diagnostic biomarkers of cervical dysplasia/neoplasia in Japanese women with a cytologic diagnosis of atypical glandular cells (AGC): a Gynecologic Oncology Group (GOG) Study.
British journal of cancer - 18 Jan 2011
Liao S-Y, Rodgers W H, Kauderer J, Bonfiglio T A, Darcy K M, Carter R, Levine L, Spirtos N M, Susumu N, Fujiwara K, Walker J L, Hatae M, Stanbridge E J
Abstract excerpt
BACKGROUND: High-risk human papillomavirus (H-HPV) infection is linked to cervical neoplasia but its role in detecting cervical glandular lesions (GLs) is unclear. Carbonic anhydrase IX (CA-IX) is a hypoxic biomarker that is highly expressed in neoplastic cervical GLs. The diagnostic utility of these biomarkers was evaluated by the Gynecologic Oncology Group in Japanese women with a cytological diagnosis of...
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