Article
Prospective evaluation of the Hybrid Capture 2 and AMPLICOR human papillomavirus (HPV) tests for detection of 13 high-risk HPV genotypes in atypical squamous cells of uncertain significance.
Journal of clinical microbiology - 1 Feb 2007
Halfon Philippe, Trepo Elisabeth, Antoniotti Gilles, Bernot Catherine, Cart-Lamy Philippe, Khiri Hacène, Thibaud Didier, Marron Jean, Martineau Agnès, Pénaranda Guillaume, Benmoura Dominique, Blanc Bernard
Abstract excerpt
The use of high-risk human papillomavirus (hrHPV) testing as an adjunct to cervical cytology in population-based screening programs is currently based on DNA hybridization and PCR assays. The aim of this study was to prospectively assess the diagnostic performance of the Hybrid Capture 2 test (HC2; Digene Corporation) in comparison with that of the recently developed PCR-based AMPLICOR HPV test (Roche Molecular...
Topics
- Carcinoma, Squamous Cell
- Cervix Uteri
- DNA, Viral
- Female
- Genotype
- Humans
- Papillomaviridae
- Papillomavirus Infections
- Polymerase Chain Reaction