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Article

Conservation of enhancer location in divergent insects.

Proceedings of the National Academy of Sciences of the United States of America - 25 Aug 2009

Cande Jessica, Goltsev Yury, Levine Michael S

Abstract excerpt

Dorsoventral (DV) patterning of the Drosophila embryo is controlled by a concentration gradient of Dorsal, a sequence-specific transcription factor related to mammalian NF-kappaB. The Dorsal gradient generates at least 3 distinct thresholds of gene activity and tissue specification by the differential regulation of target enhancers containing distinctive combinations of binding sites for Dorsal, Twist, Snail, and...

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Identifiers

PMID: 19666595
DOI: 10.1073/pnas.0905754106
PMCID: PMC2732830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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