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A <i>Burkholderia pseudomallei</i> protein microarray reveals serodiagnostic and cross-reactive antigens

28 Jul 2009

Abstract excerpt

Understanding the way in which the immune system responds to infection is central to the development of vaccines and many diagnostics. To provide insight into this area, we fabricated a protein microarray containing 1,205 Burkholderia pseudomallei proteins, probed it with 88 melioidosis patient sera, and identified 170 reactive antigens. This subset of antigens was printed on a smaller array and probed with a...

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PMID: 19666533
DOI: 10.1073/pnas.0812080106

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