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Article

The genetic and molecular basis of O-antigenic diversity in Burkholderia pseudomallei lipopolysaccharide.

PLoS neglected tropical diseases - 1 Jan 2012

Tuanyok Apichai, Stone Joshua K, Mayo Mark, Kaestli Mirjam, Gruendike Jeffrey, Georgia Shalamar, Warrington Stephanie, Mullins Travis, Allender Christopher J, Wagner David M, Chantratita Narisara, Peacock Sharon J, Currie Bart J, Keim Paul

Abstract excerpt

Lipopolysaccharide (LPS) is one of the most important virulence and antigenic components of Burkholderia pseudomallei, the causative agent of melioidosis. LPS diversity in B. pseudomallei has been described as typical, atypical or rough, based upon banding patterns on SDS-PAGE. Here, we studied the genetic and molecular basis of these phenotypic differences. Bioinformatics was used to determine the diversity of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22235357
DOI: 10.1371/journal.pntd.0001453
PMCID: PMC3250505

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