From crystal structure to <i>in silico</i> epitope discovery in the <i>Burkholderia pseudomallei</i> flagellar hook‐associated protein FlgK

Abstract excerpt

Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a potentially fatal infection that is endemic in Southeast Asia and Northern Australia that is poorly controlled by antibiotics. Research efforts to identify antigenic components for a melioidosis vaccine have led to the identification of several proteins, including subunits forming the flagella that mediate bacterial motility, host...

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