Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease: New data and meta-analysis.

doi:10.1002/ajmg.b.30986

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Article

Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease: New data and meta-analysis.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2010

Fukumoto Noriko, Fujii Takashi, Combarros Onofre, Kamboh M Ilyas, Tsai Shin-Jen, Matsushita Sachio, Nacmias Benedetta, Comings David E, Arboleda Humberto, Ingelsson Martin, Hyman Bradley T, Akatsu Hiroyasu, Grupe Andrew, Nishimura Agnes Lumi, Zatz Mayana, Mattila Kari M, Rinne Juha, Goto Yu-ichi, Asada Takashi, Nakamura Shun, Kunugi Hiroshi

Abstract excerpt

Conflicting results have been reported as to whether genetic variations (Val66Met and C270T) of the brain-derived neurotrophic factor gene (BDNF) confer susceptibility to Alzheimer's disease (AD). We genotyped these polymorphisms in a Japanese sample of 657 patients with AD and 525 controls, and...

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PMID: 19504537
DOI: 10.1002/ajmg.b.30986

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19504537-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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