Article
Chemoresponsiveness associated with canonical molecular changes in colorectal adenocarcinomas.
Anticancer research - 1 Aug 2009
Kim Jin C, Roh Seon A, Cho Dong H, Kim Tae W, Yoon Sang N, Kim Chan W, Yu Chang S, Kim Seon Y, Kim Yong S
Abstract excerpt
BACKGROUND: The canonical molecular changes in colorectal tumorigenesis were assessed for correlation with response to chemotherapy, in order to identify candidate markers. PATIENTS AND METHODS: In total, 156 patients received adjuvant postoperative fluoropyrimidine-based chemotherapy and 32 patients received oxaliplatin- or irinotecan-based chemotherapy following palliative surgery or for metastatic or recurrent...
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