Article
Effects of ooplasm transfer on paternal genome function in mice.
Human reproduction (Oxford, England) - 1 Nov 2009
Liang Cheng-Guang, Han Zhiming, Cheng Yong, Zhong Zhisheng, Latham Keith E
Abstract excerpt
BACKGROUND: The ooplasm plays a central role in forming the paternal pronucleus, and subsequently in regulating the expression of paternally inherited chromosomes. Previous studies in mice have revealed genetic differences in paternal genome processing by ooplasm of different genotypes. Ooplasm donation coupled to intracytoplasmic sperm injection (ICSI) has been used in human assisted reproductive technology...
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