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Article

Ooplasmic donation in humans: The potential for epigenic modifications

1 Apr 2002

Abstract excerpt

Ooplasm donation, wherein ooplasm is transferred from a donor oocyte to a recipient oocyte in an effort to increase embryo viability, has been applied in the human, with resulting pregnancies and births. Neither the safety nor efficacy of this method has been adequately investigated. Mitochondrial heteroplasmy in the blood of children conceived using ooplasm donation has recently been described. A follow-up study...

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PMID: 11925371
DOI: 10.1093/humrep/17.4.850

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