Article
An excess of rare genetic variation in ABCE1 among Yorubans and African-American individuals with HIV-1.
Genes and immunity - 1 Dec 2009
Crawford D C, Zheng N, Speelmon E C, Stanaway I, Rieder M J, Nickerson D A, McElrath M J, Lingappa J
Abstract excerpt
Signatures of natural selection occur throughout the human genome and can be detected at the sequence level. We have re-sequenced ABCE1, a host candidate gene essential for HIV-1 capsid assembly, in European- (n=23) and African-descent (Yoruban; n=24) reference populations for genetic variation d...
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