Article
The frequency spectrum of chromatin accessibility in Yorubans points toward a significant role of random genetic drift in shaping the chromatin landscape
2016-08-10
Abstract excerpt
The function of non-coding variation in the human genome is hotly debated. While much of the genome appears to be involved in some kind of molecular activity, a relatively small portion of the genome appears to be conserved across mammalian species. To try to understand part of this seeming paradox, we examined chromatin accessibility as a model molecular phenotype. We modeled chromatin state as either open or clo...
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Identifiers and source
- Literature Corpus work
- 9c0bedf6-6cdb-5528-bfd9-ff03a88050da
- DOI
- 10.1101/068718