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Elucidation of the transmission of a novel mutation in BRCA1 (1125delCT) in a family with multiple cases of breast cancer.

Cancer genomics & proteomics - 1 Jan 2000

Razis Evangelia, Belogianni Ioulia, Siamanta Vagia, Apessos Angela, Kyriakopoulou Vanessa, Papadopoulou Eirini, Sariyanni Mahi, Theofilopoulos Dionysios, Labropoulos Stefanos, Nasioulas Georgios

Abstract excerpt

In a family with multiple members affected by breast cancer we identified the novel mutation 1125delCT (exon 11) in BRCA1. Three out of three offsprings have the novel mutation while the mother affected by breast cancer does not carry the mutation. Linkage analysis revealed the transmission of th...

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PMID: 19656998

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19656998-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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