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Article

The frequent BRCA1 mutation 1135insA has multiple origins: a haplotype study in different populations.

BMC medical genetics - 1 Mar 2006

Rudkin Teresa M, Hamel Nancy, Galvez Maria, Hogervorst Frans, Gille Johan J P, Møller Pål, Apold Jaran, Foulkes William D

Abstract excerpt

BACKGROUND: Analysis of the chromosomal background upon which a mutation occurs can be used to reconstruct the origins of specific disease-causing mutations. The relatively common BRCA1 mutation, 1135insA, has been previously identified as a Norwegian founder mutation. We performed haplotype anal...

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Identifiers

PMID: 16509964
DOI: 10.1186/1471-2350-7-15
PMCID: PMC1403746

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-16509964-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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