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Article

CD26 expression on T cell lines increases SDF-1-α-mediated invasion

4 Aug 2009

Abstract excerpt

BACKGROUND: CD26 is a multifunctional membrane-bound glycoprotein that regulates tumour growth in addition to its other activities. Because disease aggressiveness is correlated with CD26 expression in several T-cell malignancies, we decided to investigate the invasiveness of cells expressing different levels of CD26. METHODS: To assess CD26 involvement in cell invasion, we performed in vitro invasion assays with...

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PMID: 19654580
DOI: 10.1038/sj.bjc.6605236

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