HIV-1 resistance mutations and genetic diversity among children failing antiretroviral treatment in five healthcare facilities in Benin, West Africa.

doi:10.1371/journal.pone.0317882

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Article

HIV-1 resistance mutations and genetic diversity among children failing antiretroviral treatment in five healthcare facilities in Benin, West Africa.

PloS one - 1 Jan 2025

Dagba Gbessin Edwige Hermione, Tchiakpe Edmond, Keke René Kpemahouton, Vidal Nicole, Gomgnimbou Michel Kiréopori, Sina Haziz, Adjou Euloge Senan, Afangnihoun Aldric, Bachabi Moussa, Yessoufou Akadiri, Ouedraogo Abdoul-Salam, Baba-Moussa Lamine

Abstract excerpt

BACKGROUND: Antiretroviral treatment increases the risk of accumulation of resistance mutations that negatively impact the possibilities of future treatment. This study aimed to present the frequency of HIV-1 antiretroviral resistance mutations and the genetic diversity among children with virological failure in five pediatric care facilities in Benin. METHODS: A cross-sectional study was carried out from...

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Topics

Humans
HIV-1
HIV Infections
Female
Male
Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Drug Resistance, Viral

Benin

Child, Preschool

Cross-Sectional Studies

Mutation

Genetic Variation

Infant

Anti-HIV Agents

Viral Load

Adolescent

Phylogeny

Treatment Failure

Source

Open in PubMed Open full text

Identifiers

PMID: 39879199
DOI: 10.1371/journal.pone.0317882
PMCID: PMC11778783

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