Article
Regulation of uptake of 18F-FDG by a follicular human thyroid cancer cell line with mutation-activated K-ras.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Aug 2009
Prante Olaf, Maschauer Simone, Fremont Valerie, Reinfelder Julia, Stoehr Robert, Szkudlinski Mariusz, Weintraub Bruce, Hartmann Arndt, Kuwert Torsten
Abstract excerpt
UNLABELLED: Dedifferentiation of thyroid carcinoma is accompanied by increased accumulation of the PET tracer (18)F-FDG. The molecular mechanisms responsible for this phenomenon are poorly understood. Therefore, we studied the regulation of (18)F-FDG uptake by the human follicular thyroid carcinoma cell line ML-1 and the as-yet-unknown oncogene expression of that cell line. The data obtained in ML-1 were compared...
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