Article
The NanI and NanJ Sialidases of Clostridium perfringens Are Not Essential for Virulence
4 Aug 2009
Abstract excerpt
The essential toxin in Clostridium perfringens-mediated gas gangrene or clostridial myonecrosis is alpha-toxin, although other toxins and extracellular enzymes may also be involved. In many bacterial pathogens extracellular sialidases are important virulence factors, and it has been suggested that sialidases may play a role in gas gangrene. C. perfringens strains have combinations of three different sialidase...
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