Article
The Sialidases of Clostridium perfringens type D strain CN3718 differ in their properties and sensitivities to inhibitors.
Applied and environmental microbiology - 1 Mar 2014
Li Jihong, McClane Bruce A
Abstract excerpt
Clostridium perfringens causes histotoxic infections and diseases originating in animal or human intestines. A prolific toxin producer, this bacterium also produces numerous enzymes, including sialidases, that may facilitate infection. C. perfringens type D strain CN3718 carries genes encoding three sialidases, including two large secreted sialidases (named NanI and NanJ) and one small sialidase (named NanH) that...
Topics
- Caco-2 Cells
- Clostridium perfringens
- Enzyme Inhibitors
- Enzyme Stability
- Gene Knockout Techniques
- Humans
- Hydrogen-Ion Concentration
- Metals
- Mutation
- Neuraminidase
- Temperature