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Article

A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene.

BMC genetics - 4 Aug 2009

Nakano Motoi, Miwa Nobutomo, Hirano Akiyoshi, Yoshiura Koh-Ichiro, Niikawa Norio

Abstract excerpt

BACKGROUND: Two types of cerumen occur in humans: the wet type with brownish, sticky earwax, and the dry type with a lack of or reduced ceruminous secretion. The wet type is common in populations of European and African origin, while the dry type is frequently seen in Eastern Asian populations. A...

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Source

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Identifiers

PMID: 19650936
DOI: 10.1186/1471-2156-10-42
PMCID: PMC2731057

Genes

ABCC11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19650936-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene.PMID 19650936Read ↗

A missense variant of the ABCC11 gene is associated with Axillary Osmidrosis susceptibility and clinical phenotypes in the Chinese Han Population.Semantic proximity Read ↗

Correlation of axillary osmidrosis to a SNP in the ABCC11 gene determined by the Smart Amplification Process (SmartAmp) method.Semantic proximity Read ↗

Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?Semantic proximity Read ↗

A functional ABCC11 allele is essential in the biochemical formation of human axillary odor.Semantic proximity Read ↗

Clinical and Molecular Evidence of ABCC11 Protein Expression in Axillary Apocrine Glands of Patients with Axillary Osmidrosis.Semantic proximity Read ↗

From Allelic Heterogeneity to Biomechanical Phenotypes: A Functional New Genomic Model of ABCC11 Polymorphisms and Their Role in Human Chemical EcologySemantic proximity Read ↗

Genetic influences on human body odor: from genes to the axillae.Semantic proximity Read ↗

Functional characterization of variants in human ABCC11, an axillary osmidrosis risk factor.Semantic proximity Read ↗

No evidence for an association between the earwax-associated polymorphism in ABCC11 and breast cancer risk in Caucasian women.Semantic proximity Read ↗

Association between the ABCC11 gene polymorphism and the expression of apolipoprotein D by the apocrine glands in axillary osmidrosis.Semantic proximity Read ↗

Association between breast cancer risk and the wild-type allele of human ABC transporter ABCC11.Semantic proximity Read ↗

Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence.Semantic proximity Read ↗

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