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Article

No evidence for an association between the earwax-associated polymorphism in ABCC11 and breast cancer risk in Caucasian women.

Breast cancer research and treatment - 1 Feb 2011

Beesley Jonathan, Johnatty Sharon E, Chen Xiaoqing, Spurdle Amanda B, Peterlongo Paolo, Barile Monica, Pensotti Valeria, Manoukian Siranoush, Radice Paolo, Chenevix-Trench Georgia

Abstract excerpt

ABCC11 is an ATP-binding cassette transporter responsible for the transport of a diverse range of lipophilic compounds. A single nucleotide polymorphism (SNP) encoding an amino acid change has recently been shown to determine whether cerumen (earwax) is wet or dry. We hypothesised that this ABCC1...

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Source

Identifiers

PMID: 21165769
DOI: 10.1007/s10549-010-1292-2

Genes

ABCC11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21165769-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

No evidence for an association between the earwax-associated polymorphism in ABCC11 and breast cancer risk in Caucasian women.PMID 21165769Read ↗

Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?Semantic proximity Read ↗

Association between breast cancer risk and the wild-type allele of human ABC transporter ABCC11.Semantic proximity Read ↗

The earwax-associated SNP c.538G>A (G180R) in ABCC11 is not associated with breast cancer risk in Europeans.Semantic proximity Read ↗

A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene.Semantic proximity Read ↗

Ethnic/racial and genetic influences on cerumen odorant profiles.Semantic proximity Read ↗

A Novel Association between the 27-bp Deletion and 538G>A Mutation in the ABCC11 Gene.Semantic proximity Read ↗

A SNP in the ABCC11 gene is the determinant of human earwax type.Semantic proximity Read ↗

Functional characterization of variants in human ABCC11, an axillary osmidrosis risk factor.Semantic proximity Read ↗

Allele frequencies of a SNP and a 27-bp deletion that are the determinant of earwax type in the ABCC11 gene.Semantic proximity Read ↗

Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretionSemantic proximity Read ↗

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A missense variant of the ABCC11 gene is associated with Axillary Osmidrosis susceptibility and clinical phenotypes in the Chinese Han Population.Semantic proximity Read ↗

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