Article
Association between breast cancer risk and the wild-type allele of human ABC transporter ABCC11.
Anticancer research - 1 Dec 2010
Ota Ikuko, Sakurai Aki, Toyoda Yu, Morita Satoshi, Sasaki Takeshi, Chishima Takashi, Yamakado Minoru, Kawai Yuki, Ishidao Takefumi, Lezhava Alexander, Yoshiura Koh-Ichiro, Togo Shinji, Hayashizaki Yoshihide, Ishikawa Takashi, Ishikawa Toshihisa, Endo Itaru, Shimada Hiroshi
Abstract excerpt
BACKGROUND: International mortality and frequency rates for breast cancer have been associated with the wet type of human earwax. It was recently found that earwax type is determined by a single nucleotide polymorphism (SNP), 538G>A (Gly180Arg), in ABCC11. The G allele determines the wet type of earwax as a Mendelian trait with a dominant phenotype. The present study examined the association between the frequency...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.