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Article

JAK2 and MPL gene mutations in V617F-negative myeloproliferative neoplasms.

Leukemia research - 1 Mar 2010

Siemiatkowska Anna, Bieniaszewska Maria, Hellmann Andrzej, Limon Janusz

Abstract excerpt

We report three novel mutations in JAK2 exons 12, 19 and 25 in V617F-negative patients with polycythemia vera, essential thrombocythemia and idiopathic myelofibrosis. Scanning of JAK2 exons 12-25 and MPL exon 10 revealed the presence of JAK2 alterations in six and MPL W515L/K mutations in five of...

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Source

Identifiers

PMID: 19643476
DOI: 10.1016/j.leukres.2009.06.017

Genes

JAK2
MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19643476-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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