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Article

Metastatic effect of LY-6K gene in breast cancer cells

22 Jul 2009

Abstract excerpt

The over-expression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis. As LY-6K belongs to the Ly6/uPAR superfamily, we assessed the association of LY-6K with metastasis in breast cancer cell lines and how the LY-6K gene mediates cancer cell metastasis. The migration ability of cells in which expression of LY-6K gene is up- or down-regulated was investigated...

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Identifiers

PMID: 19639180
DOI: 10.3892/ijo_00000371

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