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Article

The regulatory mechanism of the LY6K gene expression in human breast cancer cells.

The Journal of biological chemistry - 9 Nov 2012

Kong Hyun Kyung, Yoon Sukjoon, Park Jong Hoon

Abstract excerpt

LY6K is a cancer biomarker and a therapeutic target that induces invasion and metastasis. However, the molecular mechanisms that determine human LY6K transcription are completely unknown. To elucidate the mechanisms involved in human LY6K gene regulation and expression, multiple cis-elements were predicted using TRANSFAC software, and the LY6K regulatory region was identified using the luciferase assay in the...

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Identifiers

PMID: 22988241
DOI: 10.1074/jbc.M112.394270
PMCID: PMC3493930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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