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Article

Growth arrest‐specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway

21 Dec 2006

Abstract excerpt

Activation of tyrosine kinases is an important factor during cancer development. Axl, one of the receptor tyrosine kinases, binds to the specific ligand growth arrest-specific gene 6 (Gas6), which encodes a vitamin K-dependent gamma-carboxyglutamyl protein. Although many receptor tyrosine kinases and their ligands are involved in gastric carcinogenesis, whether Gas6-Axl signaling is involved in gastric...

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PMID: 17186543
DOI: 10.1002/mc.20211

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