Article
The role of red blood cell polymorphisms in resistance and susceptibility to malaria.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Apr 1999
Lell B, May J, Schmidt-Ott R J, Lehman L G, Luckner D, Greve B, Matousek P, Schmid D, Herbich K, Mockenhaupt F P, Meyer C G, Bienzle U, Kremsner P G
Abstract excerpt
In regions highly endemic for Plasmodium falciparum malaria, red cell polymorphisms that confer resistance to severe disease are widespread. Sickle cell trait, alpha-thalassemia, glucose-6-phosphate dehydrogenase deficiency, and blood groups were determined in 100 children from Gabon with severe malaria who were matched with 100 children with mild malaria and followed up for evaluation of reinfections. The sickle...
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