Article
A simple electronic tool for assessing amino acid sequence polymorphisms within exon-2 of HLA-DPB1 alleles.
Human immunology - 1 Aug 2020
Sullivan H Clifford, Gragert Loren, Smith Geoffrey H, Lindblad Kelsi, Gebel Howard M, Bray Robert A
Abstract excerpt
In November 2014, the OPTN/UNOS Board of Directors mandated that HLA-DPB1 typing be performed for all deceased donors. Currently, there are over 1,000 known HLA DPB1 alleles, yet fewer than 30 are represented on commonly used single antigen bead (SAB) solid phase antibody assays. Moreover, the official World Health Organization (WHO) nomenclature for the DPB1 locus does not permit assessment of structural...
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