Article
The role of strain variation in BAX and BCL-2 expression in murine bleomycin-induced pulmonary fibrosis.
Pakistan journal of biological sciences : PJBS - 1 Dec 2008
Safaeian L, Jafarian A, Rabbani M, Sadeghi H M, Torabinia N, Alavi S A
Abstract excerpt
This study hypothesized that the expression of apoptosis-regulatory genes, such as BCL-2 and BAX may be affected by genetic variation in bleomycin-induced pulmonary fibrosis in C57BL/6 and NMRI mice. Pulmonary fibrosis induced by single intratracheal dose of bleomycin (3 U kg(-1)). After 2 weeks,...
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