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Article

Immunologic alterations in bleomycin-treated mice: role of pulmonary fibrosis in the modulation of immune responses.

American journal of respiratory and critical care medicine - 1 Jun 1996

Zhu J, Kaplan A M, Goud S N

Abstract excerpt

Among the side effects of bleomycin (BLM), a drug frequently used in the treatment of lymphomas and squamous-cell carcinomas, is pneumonitis with pulmonary fibrosis. The most prominent biochemical lesion associated with pulmonary fibrosis, a chronic debilitating and sometimes fatal disease, is an...

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Source

Identifiers

PMID: 8665057
DOI: 10.1164/ajrccm.153.6.8665057

Genes

BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8665057-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Immunologic alterations in bleomycin-treated mice: role of pulmonary fibrosis in the modulation of immune responses.PMID 8665057Read ↗

Contribution of T lymphocytes to the development of bleomycin-induced pulmonary fibrosis.Semantic proximity Read ↗

Mechanisms of bleomycin-induced lung damageSemantic proximity Read ↗

The role of strain variation in BAX and BCL-2 expression in murine bleomycin-induced pulmonary fibrosis.Semantic proximity Read ↗

3-Methylindole-induced splenotoxicity: functional analysis of immune parameters and lymphocyte phenotyping by flow cytometry.Semantic proximity Read ↗

Qualitative Rather than Quantitative Changes Are Hallmarks of Fibroblasts in Bleomycin-Induced Pulmonary FibrosisSemantic proximity Read ↗

The Bleomycin Model of Pulmonary Fibrosis.Semantic proximity Read ↗

Toxicogenomic assessment of in vitro macrophages exposed to profibrotic challenge reveals a sustained transcriptomic immune signatureSemantic proximity Read ↗

Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis.Semantic proximity Read ↗

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