Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.

American journal of physiology. Gastrointestinal and liver physiology - 1 Oct 2009

Frei Eva, Huster Maria, Smital Petra, Schlossmann Jens, Hofmann Franz, Wegener Jörg W

Abstract excerpt

cGMP-dependent protein kinase I (cGKI) induces relaxation of smooth muscle via several pathways that include inhibition of intracellular Ca(2+) signaling and/or involve activation of myosin phosphatase. In the present study, we investigated these mechanisms comparatively in colon and jejunum long...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amides
Share to Carbachol
Share to Cyclic GMP-Dependent Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Jejunum

Share to Marine Toxins

Share to Myosin-Light-Chain Kinase

Share to Oxazoles

Share to rho-Associated Kinases

Source

Identifiers

PMID: 19628652
DOI: 10.1152/ajpgi.00095.2009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19628652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.PMID 19628652Read ↗

cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium.Semantic proximity Read ↗

Signalling by cGMP-dependent protein kinases.Semantic proximity Read ↗

Inhibition of Galphaq-dependent PLC-beta1 activity by PKG and PKA is mediated by phosphorylation of RGS4 and GRK2.Semantic proximity Read ↗

Ascending contraction and descending relaxation in the distal colon of mice lacking interstitial cells of Cajal.Semantic proximity Read ↗

Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction.Semantic proximity Read ↗

Roles of interstitial cells of Cajal in regulating gastrointestinal motility: in vitro versus in vivo studies.Semantic proximity Read ↗

A catalytically inactive mutant of type I cGMP-dependent protein kinase prevents enhancement of large conductance, calcium-sensitive K+ channels by sodium nitroprusside and cGMP.Semantic proximity Read ↗

Differential expression of multidrug resistance protein 5 and phosphodiesterase 5 and regulation of cGMP levels in phasic and tonic smooth muscle.Semantic proximity Read ↗

Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle.Semantic proximity Read ↗

Different tachykinin receptors mediate chloride secretion in the distal colon through activation of submucosal neurones.Semantic proximity Read ↗

Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.Semantic proximity Read ↗

Cyclic AMP- and cyclic GMP-dependent protein kinases differ in their regulation of cyclic AMP response element-dependent gene transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.