Article
Apolipoprotein E genotype predicts cardiovascular endpoints in dialysis patients with type 2 diabetes mellitus.
Atherosclerosis - 1 Jan 2010
Winkler Karl, Hoffmann Michael M, Krane Vera, März Winfried, Drechsler Christiane, Wanner Christoph
Abstract excerpt
OBJECTIVE: Cardiovascular disease (CVD) is the leading cause of death in patients with type 2 diabetes (T2DM) and end-stage renal disease (ESRD). Lipid metabolism is influenced by environmental and genetic factors. Among the latter, the apolipoprotein E (apoE) genotype is known to be associated with CVD risk and thus may affect cardiovascular outcome. METHODS AND RESULTS: Based on the German Diabetes and Dialysis...
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