Article
Apolipoprotein E4 reduces risk of diabetic nephropathy in patients with NIDDM.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Apr 1998
Kimura H, Suzuki Y, Gejyo F, Karasawa R, Miyazaki R, Suzuki S, Arakawa M
Abstract excerpt
Hypercholesterolemia is a major determinant of the decline of renal function in patients with diabetes. Apolipoprotein E polymorphism may influence the metabolism of lipoprotein in diabetic patients. The purpose of this study was to investigate the association between genetic polymorphisms in apo...
Topics
- Adult
- Aged
- Alleles
- Apolipoprotein E4
- Apolipoproteins E
- DNA
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Female
- Genotype
- Humans
- Kidney Failure, Chronic
- Male
- Middle Aged
- Phenotype
- Polymorphism, Genetic
- Renal Dialysis