Article
Apolipoprotein E4 reduces risk of diabetic nephropathy in patients with NIDDM.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Apr 1998
Kimura H, Suzuki Y, Gejyo F, Karasawa R, Miyazaki R, Suzuki S, Arakawa M
Abstract excerpt
Hypercholesterolemia is a major determinant of the decline of renal function in patients with diabetes. Apolipoprotein E polymorphism may influence the metabolism of lipoprotein in diabetic patients. The purpose of this study was to investigate the association between genetic polymorphisms in apolipoprotein E and the progression of diabetic nephropathy in patients with non-insulin-dependent diabetes mellitus over...
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