Article
Apo E gene polymorphism on development of diabetic nephropathy.
Cell biochemistry and function - 1 Jan 2000
Ilhan Necip, Kahraman Neslihan, Seçkin Dilara, Ilhan Nevin, Colak Ramis
Abstract excerpt
Type 2 diabetes causes premature morbidity and mortality due to the complications of atherosclerosis and diabetic nephropathy (DN). Polymorphism of Apo E gene is known to influence lipid metabolism. Apo E is polymorphic, consisting of three common isoforms (epsilon2, epsilon3 and epsilon4) encoded by three alleles (2, 3 and 4) in exon 4 on chromosome 19. The aim of this study was to investigate the effect of Apo...
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